Which response would NOT be expected in the first minutes of acute inflammation?

During the initial phases of acute inflammation, the body undergoes several key physiological changes. Vasodilation, or the widening of blood vessels, occurs rapidly in response to inflammatory mediators. This process increases blood flow to the affected area, which is essential for delivering immune cells and nutrients needed to combat injury or infection.

Pain sensation is also an expected response in the early stages of acute inflammation. The release of chemical mediators like prostaglandins and bradykinin sensitizes nerve endings, leading to the sensation of pain, which may serve as a protective mechanism to prevent further injury.

Neutrophil migration, the movement of these key white blood cells to the site of inflammation, is another characteristic event. This process begins shortly after the onset of inflammation as neutrophils are attracted to the area by various signals including chemokines.

Reduced blood flow, however, does not align with the typical early responses of acute inflammation. Instead, the initial response features increased blood flow due to vasodilation and increased vascular permeability. Thus, a decrease in blood flow would be counterproductive in the context of acute inflammation, making it the unexpected response in the first minutes of this process.