Which of the following symptoms is primarily associated with the advanced stages of Parkinson's disease?

In advanced stages of Parkinson's disease, multiple motor symptoms can manifest, contributing to a significant decline in a patient’s overall functional abilities. Each of the symptoms provided plays a role in the progression of the disease.

Severe rest tremor is commonly observed in many Parkinson’s patients, particularly in the early to mid-stages. However, as the disease progresses to advanced stages, tremors may become less prominent in some patients, overshadowed by other debilitating symptoms.

Bradykinesia, characterized by slowness of movement, impacts various aspects of daily life and becomes more pronounced as the disease advances. Patients often experience difficulty initiating movement and exhibit reduced spontaneous movement, contributing to a notable decrease in the ability to perform daily activities.

Postural instability emerges as a significant concern in the later stages of Parkinson's disease. This symptom leads to balance problems, increasing the risk of falls—a major health risk for individuals with the condition. As the disease advances, the inability to maintain posture becomes more critical, impacting mobility and independence.

The choice indicating “all of the above” highlights the fact that each of these symptoms can coexist in the advanced stages of Parkinson’s disease. As the disease progresses, patients often experience a combination of severe rest tremor, brady