Which of the following is NOT true regarding SLE?

Systemic lupus erythematosus (SLE) is an autoimmune condition that indeed shows a pronounced gender disparity, predominantly affecting women more than men. This attribute underlines the hormonal and genetic factors contributing to the disease's prevalence in females.

Another critical aspect of SLE is the association with ocular manifestations, one of the most prevalent being dry eyes. This dryness results from the inflammatory process characteristic of SLE, affecting the lacrimal glands and other structures involved in tear production and maintenance, leading to a chronic dry eye condition.

The antinuclear antibody (ANA) test plays a significant role in the diagnosis of SLE. A positive ANA test, while not exclusive to SLE, indicates a broader autoimmune process and is a common starting point in evaluating suspected cases of this condition.

In terms of rashes, SLE is well-known for causing a variety of skin manifestations, including a "butterfly" rash across the cheeks and nose, rather than a bullseye rash. The description of a bullseye rash is typically associated with Lyme disease, not SLE. Therefore, the correct assertion is that SLE does not present with a bullseye rash, a key differentiation that highlights the distinctive clinical presentations of various autoimmune and