Which of the following is NOT part of Virchow's triad when explaining the causes of a venous thromboembolism (VTE)?

Prepare for the NBEO Systemic Disease Exam. Use flashcards and multiple-choice questions to test your knowledge. Each question includes hints and explanations. Enhance your understanding and readiness for the exam.

Virchow's triad consists of three key factors that contribute to the formation of venous thromboembolism (VTE): stasis of blood flow, vascular endothelial injury, and hypercoagulable states.

In this context, stasis of blood flow refers to conditions where blood flow is significantly reduced, leading to increased clot formation. Vascular endothelial injury encompasses damage to the blood vessel lining, which can promote thrombus formation due to exposure of underlying collagen and tissue factor. A hypercoagulable state refers to an increased tendency of the blood to clot, which can arise from various conditions such as certain genetic disorders, malignancy, or prolonged immobilization.

The concept of a hypocoagulable state, which suggests a tendency for decreased clot formation or increased bleeding risk, does not align with the mechanisms of VTE as outlined in Virchow's triad. Instead, this state would typically lead to a reduced risk of thrombus development, making it an inappropriate factor in the context of VTE causes. Therefore, this option is accurately identified as not part of Virchow's triad, since it represents a condition opposite to what promotes venous thrombosis.

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