Which of the following is NOT associated with Marfan's syndrome?

Prepare for the NBEO Systemic Disease Exam. Use flashcards and multiple-choice questions to test your knowledge. Each question includes hints and explanations. Enhance your understanding and readiness for the exam.

Marfan's syndrome is a genetic disorder that affects connective tissue and is characterized by several distinct features. Individuals with Marfan's syndrome typically present as tall with long limbs and fingers, which is a result of the abnormal growth patterns associated with the condition. This characteristic aligns with the first choice.

Moreover, Marfan's syndrome follows an autosomal dominant inheritance pattern. This means that only one copy of the mutated gene inherited from an affected parent can cause the disorder, which is consistent with the second choice.

Another hallmark of Marfan's syndrome is the ocular manifestation of lens subluxation, where the crystalline lens displaces from its normal position. This condition occurs due to the weakening of the connective tissue structures that support the lens.

In contrast, neurofibromas are not associated with Marfan's syndrome. They are typically seen in Neurofibromatosis, a different genetic disorder characterized by the development of tumors on nerve tissue, and thus, this statement does not relate to Marfan's syndrome. This is why the option regarding neurofibromas is identified as the correct response, as it distinctly does not fit the profile of conditions linked to Marfan's syndrome.

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