Which of the following is NOT associated with Ankylosing Spondylitis?

Ankylosing spondylitis is a chronic inflammatory disease primarily affecting the spine and the sacroiliac joints, leading to progressive stiffness and pain. The distinctive symptoms associated with ankylosing spondylitis include:

• Non-granulomatous anterior uveitis, which is a common extra-articular manifestation of the disease. This condition can present with eye pain, redness, and photophobia, indicating the involvement of the uvea.

• Lower back pain that worsens with rest is a hallmark symptom of ankylosing spondylitis. The pain is often alleviated with exercise, which is contrary to the notion that it worsens with exercise. This characteristic pain pattern is significant in diagnosing this condition.

• The "bamboo spine" refers to the radiographic finding seen in advanced cases of ankylosing spondylitis, where the vertebrae become fused and align in such a way that they resemble bamboo.

• The presence of the HLA-B27 antigen is a well-established association with ankylosing spondylitis, as a significant percentage of patients with this condition test positive for this genetic marker.

Understanding these associations clarifies that the correct answer to the question is indeed the option that