Which of the following is NOT true when comparing Nephritic Syndrome vs Nephrotic Syndrome?

In comparing nephritic syndrome and nephrotic syndrome, the statement that nephrotic syndrome is more associated with hypertension is not true. While both conditions involve kidney dysfunction and can potentially lead to varying degrees of hypertension, nephritic syndrome is more commonly associated with hypertension due to its inflammatory processes and fluid overload, which can increase blood pressure.

Nephrotic syndrome primarily involves heavy proteinuria, hypoalbuminemia, and edema, rather than significant hypertension. The primary clinical features of nephrotic syndrome center around the massive loss of proteins in the urine, leading to low serum albumin levels and resultant edema, rather than the hypertension seen in nephritic syndrome.

Understanding the core differences between the two syndromes is crucial, as nephritic syndrome often presents with hematuria and can involve some level of proteinuria, but not to the extent observed in nephrotic syndrome. Nephritic syndrome is also marked by inflammation of the glomerulus, which explains the symptoms of hematuria and hypertension, while nephrotic syndrome, though also involving glomerular issues, is characterized predominantly by significant protein loss without the same degree of inflammatory response.