Which of the following is NOT considered an inherited hypercoagulable state?

Thrombocytopenia is a condition characterized by a decrease in the number of platelets in the blood. While it can lead to various bleeding issues, it is not classified as a hypercoagulable state. Instead, hypercoagulability refers to a tendency of the blood to clot more easily than normal, which can be due to various factors, including inherited conditions.

In contrast, the factor V Leiden mutation, protein C and S deficiency, and antithrombin III deficiency are all recognized inherited disorders that predispose individuals to venous thrombosis. Each of these conditions leads to an increased risk of clot formation through different mechanisms. For example, the factor V Leiden mutation causes resistance to activated protein C, leading to unchecked thrombin generation. Protein C and S deficiencies disrupt the body's natural anticoagulation processes, while antithrombin III deficiency impairs the inhibition of thrombin and other proteases involved in clotting.

Thus, thrombocytopenia is not associated with increased clot formation in the same way that these inherited conditions are, making it the correct response to the question regarding which is NOT considered an inherited hypercoagulable state.