Which of the following conditions is NOT associated with Obstructive Sleep Apnea?

Floppy iris syndrome is not typically associated with obstructive sleep apnea (OSA). This condition is primarily related to the use of certain medications, particularly alpha-blockers, and it occurs during cataract surgery, making the iris floppy and more difficult to operate on. The relationship between floppy iris syndrome and OSA is not established in the literature.

On the other hand, conditions like increased risk for hypertension, normal tension glaucoma, and non-arteritic anterior ischemic optic neuropathy (NAION) can present as complications associated with OSA. OSA causes intermittent hypoxia and leads to a number of systemic effects, including an increased risk of developing hypertension due to heightened sympathetic nervous system activity. Additionally, there is evidence suggesting a potential link between OSA and normal tension glaucoma, as the intermittent elevations in intracranial pressure during apneic episodes might influence optic nerve health. NAION is also linked to OSA due to potential ischemic events caused by blood flow disruptions during apneic periods.

In summary, while the other conditions are recognized associations with obstructive sleep apnea due to their mechanical or vascular implications, floppy iris syndrome does not share this connection, making it the exception in this context.