Which of the following benign skin lesions are typically associated with hyperlipidemia?

Xanthelasma is a type of benign skin lesion that is typically associated with hyperlipidemia. These lesions appear as soft, yellowish plaques that often develop on the eyelids or around the eyes and are caused by lipid deposits in the skin. The presence of xanthelasma often serves as a clinical indicator of underlying lipid disorders, including elevated cholesterol levels, which are part of hyperlipidemia.

The other choices refer to different skin lesions that do not have a direct connection to hyperlipidemia. Seborrheic keratosis, for instance, is a common benign growth that is not associated with lipid levels and typically appears as a wart-like lesion. Keratoacanthoma is also a benign tumor that resembles squamous cell carcinoma but is more related to sun exposure than to lipid metabolism. Lastly, papillomas are benign epithelial tumors often related to viral infections, particularly the human papillomavirus (HPV), rather than being linked to lipid levels.

In summary, the association of xanthelasma with hyperlipidemia makes it the correct answer, highlighting its role as a potential physical sign of lipid metabolism disorders.