Which congenital condition would most likely result in interstitial keratitis in the baby?

Prepare for the NBEO Systemic Disease Exam. Use flashcards and multiple-choice questions to test your knowledge. Each question includes hints and explanations. Enhance your understanding and readiness for the exam.

Interstitial keratitis is a condition characterized by inflammation of the corneal stroma, leading to opacity and other changes in the cornea. Among the congenital conditions listed, syphilis is known to cause interstitial keratitis, particularly when the infection is transmitted from mother to child during pregnancy.

Congenital syphilis can lead to a spectrum of ocular abnormalities, including interstitial keratitis, due to the involvement of the corneal tissue by the treponema bacteria. The inflammation resulting from syphilitic involvement can lead to characteristic ocular findings, including keratitis.

In contrast, fetal alcohol syndrome is associated primarily with a range of developmental issues including facial dysmorphisms and neurological deficits, but does not typically cause interstitial keratitis. Similarly, toxoplasmosis can lead to retinal damage and other ocular issues, but corneal involvement such as interstitial keratitis is not a known complication. Cerebral palsy is a neurological condition resulting from brain damage and is not linked to keratitis or direct ocular findings.

Thus, among the options, syphilis is the only congenital condition that prominently associates with interstitial keratitis, making it the correct answer.

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