Which autosomal dominant condition would most likely require a subsequent colonoscopy?

Prepare for the NBEO Systemic Disease Exam. Use flashcards and multiple-choice questions to test your knowledge. Each question includes hints and explanations. Enhance your understanding and readiness for the exam.

Familial Adenomatous Polyposis (FAP) is an autosomal dominant condition characterized by the development of numerous polyps in the colon and rectum, which, if left untreated, have a nearly 100% risk of progressing to colorectal cancer. Individuals with FAP typically begin to develop these polyps during their teenage years or early adulthood. Due to this high predisposition to colorectal cancer, regular surveillance through colonoscopy is essential for early detection and management of any polyps. The standard recommendation is to start colonoscopies at a young age and then continue them at regular intervals, usually every 1 to 2 years, depending on the number and type of polyps found.

Other conditions listed, such as Marfan's syndrome, Huntington's Chorea, and Neurofibromatosis Type 1, do not have the same significant and direct relation to colorectal cancer surveillance. While patients with Marfan's syndrome may have associated gastrointestinal issues, they do not have a direct link to colonic polyp formation requiring frequent colonoscopy. Huntington's Chorea involves neurological degeneration and does not typically necessitate a colonoscopy either. Neurofibromatosis Type 1 is associated with skin and neurological manifestations, where the risk of malignancy

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