What ocular condition is most commonly seen in patients with SLE?

In patients with systemic lupus erythematosus (SLE), dry eye syndrome is the ocular condition most commonly observed. This association stems from the systemic nature of SLE, where various autoimmune processes can lead to lacrimal gland dysfunction. This results in decreased tear production, leading to the symptoms of dry eye, such as irritation, discomfort, and visual disturbances.

SLE can also be associated with other ocular conditions, but dry eye syndrome is particularly prevalent due to its connection to autoimmune profiles, leading to increased inflammation in the lacrimal glands. The multifactorial nature of SLE additionally contributes to the likelihood of patients experiencing dry eyes as part of their systemic symptoms, making it a more frequent complaint compared to other conditions listed.

For instance, while uveitis does occur in SLE patients, it is less common than dry eye syndrome. Similarly, retinal detachment and conjunctivitis may be present in some cases, but they are not as frequently reported or as characteristic of SLE as dry eye. Thus, recognizing the prominence of dry eye syndrome in SLE helps in the comprehensive management of these patients.