What is the consequence of untreated atherosclerosis in coronary arteries?

When atherosclerosis occurs in the coronary arteries and remains untreated, the primary consequence is a myocardial infarction, commonly known as a heart attack. This condition arises when plaque buildups in the coronary arteries lead to narrowing and possibly complete blockage of these vital blood vessels. As a result, the heart muscle is deprived of oxygen-rich blood, which can cause damage or death to the heart tissue.

In situations where a plaque ruptures, it can trigger a blood clot that fully occludes the artery, leading to acute ischemia of the heart muscle. The manifestation of this ischemia is often expressed through chest pain (angina) or, in more severe cases, a myocardial infarction.

Although untreated atherosclerosis can have systemic implications such as increasing the risk for strokes, peripheral vascular disease, and other forms of heart disease, the immediate and direct consequence of untreated atherosclerosis specifically in the coronary arteries aligns with myocardial infarction. This underscores the critical importance of early detection and management of atherosclerosis to prevent severe cardiovascular events.