What is the classic triad of Reactive Arthritis?

The classic triad of Reactive Arthritis consists of urethritis, uveitis, and arthritis. Reactive Arthritis is an autoimmune condition that typically occurs following an infection, particularly involving the genitourinary or gastrointestinal systems.

Urethritis refers to inflammation of the urethra, which can be seen in individuals who have had certain infections such as chlamydia. Uveitis, or inflammation of the uveal tract of the eye, can present as eye pain, redness, and vision changes. Finally, arthritis, characterized by joint pain and swelling, is a hallmark symptom of this condition.

Each of these components plays a significant role in the disease process of Reactive Arthritis, reflecting the interplay between infection and the subsequent immune response. Understanding this triad is essential for clinicians to recognize and diagnose Reactive Arthritis accurately, especially since it can be confused with other forms of arthritis like rheumatoid arthritis or other spondyloarthropathies.