What is NOT part of the classic triad of Neurofibromatosis type 1?

Prepare for the NBEO Systemic Disease Exam. Use flashcards and multiple-choice questions to test your knowledge. Each question includes hints and explanations. Enhance your understanding and readiness for the exam.

Neurofibromatosis type 1 (NF1) is characterized by a classic triad of findings that include café au lait spots, neurofibromas, and Lisch nodules. Café au lait spots are flat, tan-colored skin lesions that are typically present at birth or develop during early childhood. Neurofibromas are benign tumors that arise from the nerve sheath and often appear later in life, commonly manifesting as soft, fleshy growths that can occur anywhere on the body. Lisch nodules are harmless hamartomas of the iris that become apparent during childhood and are a distinct and helpful diagnostic criterion for NF1.

Acoustic neuroma, on the other hand, is associated with Neurofibromatosis type 2 (NF2) rather than NF1. NF2 primarily involves bilateral vestibular schwannomas (often referred to as acoustic neuromas), which affect hearing and balance. Therefore, acoustic neuroma does not fit within the classic triad of NF1 findings, distinguishing it clearly from the other listed features that are typical in NF1.

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