What does the pneumonic TDOME help remember regarding conditions associated with keratoconus?

The mnemonic TDOME is used to remember conditions that are associated with keratoconus. While all the listed options may have associations with various ocular or systemic conditions, Turner's syndrome is the correct association when it comes to keratoconus.

Keratoconus is a degenerative condition of the cornea characterized by thinning and cone-like protrusion. Research suggests an increased prevalence of keratoconus in patients with specific genetic and systemic disorders. Turner's syndrome, a condition caused by a missing or incomplete X chromosome in females, has been noted to have a higher incidence of keratoconus among its associated ocular features.

The other conditions, while they may also have ocular manifestations, are not typically associated with keratoconus in the same way. For instance, Down syndrome has its own set of common eye problems but is not primarily linked to keratoconus. Similarly, osteogenesis imperfecta and Marfan's syndrome have distinct ocular findings, such as blue sclera in osteogenesis imperfecta and lens dislocation in Marfan's syndrome, but neither has a significant direct relationship with keratoconus.

Thus, recognizing Turner's syndrome as part of the TDOME mnemonic specifically highlights the association relevant to keratocon