Spina bifida is a neural tube defect associated with which vitamin deficiency?

Spina bifida, a type of neural tube defect, is closely linked to folic acid deficiency. Folic acid, also known as vitamin B9, is crucial for proper neural development in the early stages of pregnancy. Adequate levels of folate are necessary for the closure of the neural tube, which occurs within the first month after conception. Insufficient folic acid during this critical period can lead to defects such as spina bifida, where the spinal cord does not close completely.

Numerous studies have highlighted the importance of folic acid supplementation for women of childbearing age, as it significantly reduces the risk of neural tube defects. This is why it is strongly recommended for pregnant women or those planning to become pregnant to ensure they have adequate folate levels. In summary, the association of spina bifida with a deficiency of folic acid underlines the vitamin's vital role in neurodevelopment and the prevention of congenital abnormalities.