Alcoholic Hepatitis is likely to show a significant increase in which two liver enzymes?

Alcoholic hepatitis is characterized by liver inflammation due to excessive alcohol consumption, and it is associated with specific changes in liver enzyme levels. The primary markers for liver damage in this condition are aspartate aminotransferase (AST) and alanine aminotransferase (ALT).

In alcoholic hepatitis, there is typically a significant increase in AST levels relative to ALT levels, often with an AST to ALT ratio greater than 2:1. This is a classic laboratory finding that helps clinicians identify and diagnose the condition. The elevation of these enzymes indicates hepatocyte injury, which occurs due to the toxic effects of alcohol on liver cells.

While other enzymes may also be elevated in alcoholic liver disease, the significant elevation of AST and ALT in the context of alcoholic hepatitis is the hallmark of this condition, making it the most relevant choice for this question. Understanding this relationship is crucial for the clinical assessment and management of patients with liver disease due to alcohol.