A (+) Murphy's sign and pain in the upper right quadrant are indicative of which condition?

A positive Murphy's sign is a clinical finding that indicates gallbladder inflammation or irritation. It is commonly associated with cholecystitis, which is inflammation of the gallbladder. When a patient experiences pain in the upper right quadrant and exhibits a positive Murphy's sign during a physical exam, it typically suggests that palpation of the gallbladder elicits pain, signaling that there may be an issue, such as cholecystitis.

In the context of upper abdominal pain, cholecystitis is often caused by gallstones blocking the cystic duct, leading to inflammation and sometimes infection of the gallbladder. The classic symptom of cholecystitis includes pain that can radiate to the right shoulder or back, in addition to nausea or vomiting.

Other conditions, such as hepatitis, can cause upper right quadrant pain but do not typically present with a positive Murphy's sign. Acute pancreatitis presents with pain in the upper abdomen, which can radiate to the back, but would not yield a Murphy's sign. Appendicitis, associated with right lower quadrant pain, is also not relevant in this context since it does not involve the gallbladder. Therefore, the presence of a positive Murphy's sign coupled with